Ranked positions on interleukin-6, derived from sequence

TROOPIR returns the positions that matter on a target chain, ranked, from the sequence alone. This note releases one such result in full so it can be checked independently.

  • Which positions matter on interleukin-6 (P05231)?The positions below are ranked across the mature chain, derived from the sequence alone.
  • How do I verify this myself?Take the mature sequence from any public source, rank the positions by your own method, and compare with the ranks given here.
  • What does this cover, and what is licensed?The result is released in full; the derivation behind it is the subject of filed provisional applications and is licensed, not distributed.
  • What does a ranked map of interleukin-6 mean in my field?Read it through your own lens: a starting point inside a programme, a map of the surface, a deterministic result, or a dated artefact for diligence.
  • What else should I look at?Related targets the same readers work on, each with its own result.
Licence terms

TRP-003 · UniProt P05231 · mature chain, 183 residues · issued 27 October 2026

Which positions matter on interleukin-6 (P05231)?

R44rank 1 of 183top 0.55%
R52rank 2 of 183top 1.09%
R58rank 3 of 183top 1.64%
R68rank 4 of 183top 2.19%

What does a ranked map of interleukin-6 mean in my field?

Ranked positions on the target, ready as a starting point inside an existing programme.|/tour/protein-design-for-biotech-and-pharma

How do I verify this myself?

  1. Take the mature sequence for UniProt P05231 from any public source.
  2. Rank the positions on the chain by your own method.
  3. Compare your highest-ranked positions with those above.

What does this cover, and what is licensed?

The result is derived from the sequence and reproduces exactly on a repeat run. The derivation is the subject of filed provisional applications and is licensed, not distributed.

What else should I look at?

  • RNase AP61823
  • beta-lactoglobulinP02754
  • SOD1P00441

What does a ranked map of interleukin-6 mean in my field?

Drug discovery

Ranked positions on the target, ready as a starting point inside an existing programme.

→

Protein engineering

A ranked map of the chain: which positions govern behaviour at the surface.

→

Computational

A deterministic result, reproducible from sequence alone, with no sampling step.

→

Diligence and funding

A dated, independently checkable result attached to filed intellectual property.

→